Common side effects of Tamoxifen include hot flashes, changes in menstrual period, and vaginal dryness. Other less common side-effects include loss of appetite, vaginal itching, and vaginal discharge. Tamoxifen also slightly increases your risk of uterine cancer and blood clots.

If this drug is prescribed for you, potential side effects will be monitored closely.

Tamoxifen has also been found to reduce the risk of getting breast cancer. In some cases, it has been given to healthy women who are at high risk of getting breast cancer. Research continues on the use of this drug and others to prevent breast cancer in high risk women.