When you talk about chemotherapy, they're very quick to tell you about all of the anti-nausea medicine that will help control the adverse effects. In my situation, they didn't work all the time. I experienced nausea and diarrhea. The positive part is that I lost twenty some pounds, and that despite the fact that I lost my hair I didn't have to shave my legs, so we decided that was a positive. High doses chemotherapy - its an invasion on your body. Its meant to kill cells. It makes you sick. Would I go through chemotherapy again if it was determined that I needed it? I wouldn't look forward to it, but yeah, I would do it again.